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Angela Kadenhe-Chiweshe, MD

Positions and Appointments

2009-present  Assistant Professor of Surgery
Columbia University College of Physicians and Surgeons , New York, NY
2009-present  Attending Surgeon
Morgan Stanley Children's Hospital of NewYork-Presbyterian/Columbia, New York, NY

Clinical Specialties

Neonatal surgery
Gastrointestinal surgery
Thoracic surgery
Minimal access surgery

Research Interests

Tumor angiogenesis
Mechanisms of resistance to angiogenic therapies

Education and Training

2007-2009  Pediatric Surgery Fellowship
Morgan Stanley Children's Hospital of NewYork-Presbyterian/Columbia, New York NY
2004-2007  General Surgery Residency
Morgan Stanley Children's Hospital of NewYork-Presbyterian/Columbia, New York, NY
2003-2004  Postdoctoral Clinical Fellowship--ECMO
Morgan Stanley Children's Hospital of NewYork-Presbyterian/Columbia, New York, NY
2001-2002  Postdoctoral Research Fellowship--Pediatric Tumor Biology
Columbia University College of Physicians and Surgeons, New York, NY
1995-1999  MD
Milton S. Hershey College of Medicine, The Pennsylvania State University, Hershey, PA
1991-1994  BS
College of Natural Sciences and Mathematics, Indiana University of Pennsylvania, Indiana, PA

Board Certifications

New York State Licensure 3/2008

American Board of Surgery – Board Certification in General Surgery 5/2009

Professional Honors

Blakemore Prize 2004
Awarded by the Department of Surgery for outstanding research

Selected Publications

Kadenhe-Chiweshe A, Papa J, McCrudden KW, Frischer, Bae JO, Huang J, Fisher J, Lefkowitch JH, Feirt N, Rudge J, Holash J, Yancopoulos GD, Kandel JJ, Yamashiro DJ. Sustained VEGF blockade results in microenvironmental sequestration of VEGF by tumors and persistent VEGF receptor-2 activation. Molecular Cancer Research. 2008 Jan: 6(1):1-9.

Middlesworth WM, Kadenhe-Chiweshe A.Neonatal Intestinal Obstruction Burg/Ingelfinger/Polin/Gershon: Current Pediatric Therapy 18th Revised edition, 2006.

Frischer JS, Huang J, Serur A, Kadenhe-Chiweshe A, McCrudden KW, O’Toole K, Holash J, Yancopoulous GD, Yamashiro DJ, Kandel JJ. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. International Journal of Oncology, September 2004. 25 (3): p.549-553.

Frischer JS, Huang J, Serur A, Kadenhe A, Yamashiro DJ, Kandel JJ. Biomolecular markers and involution of hemangiomas. Journal of Pediatric Surgery, March 2004. 39(3): p. 400-4.

Kaicker S, McCrudden KW, Beck L, New T, Huang J, Frischer JS, Serur A, Kadenhe-Chiweshe A, Yokoi A, Kandel JJ, Yamashiro DJ. Thalidomide Is Anti-Angiogenic In A Xenograft Model of Neuroblastoma. International Journal of Oncology, December 2003. 23 (6): p.1651-1656.

Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O'Toole K, Stolar CJH, Zabski S, et al. Regression of Established tumors and Metastases by potent VEGF Blockade. Proceedings of the National Academy of Science. June 2003. p. 7785-7790.

McCrudden KW, Hopkins B, Frischer J, Novikov A, Huang J, Kadenhe A, New T, Yokoi A. Yamashiro, D.J., Kandel, J.J., Middlesworth, W. Anti-VEGF Antibody in Experimental Hepatoblastoma: Suppression of Tumor Growth and Altered Angiogenesis. Journal of Pediatric Surgery, March 2003. 38(3): p. 308-314.


Kadenhe-Chiweshe A, Bae J, Kandel JJ, Yamashiro DJ.Matrix-growth factor interaction: a novel mechanism of tumor vessel recovery during VEGF blockade. Oral Presentation: American Academy of Pediatrics 2005 National Conference and Exhibition Washington, DC, October 2005.

Kadenhe-Chiweshe A, Frischer JS, Bae J, Huang J, Kandel JJ, Yamashiro DJ. Tumor inhibition corresponds to perturbation and recovery of vasculature during sustained potent VEGF blockade. Oral Presentation: 36th Annual Meetings of the American Pediatric Surgical Association (APSA) Phoenix, AZ, May 2005.

Kadenhe-Chiweshe A, Ullner P, Bae J, Ferrari E, Popilskis S, Yamashiro DJ, Kandel JJ. Generation of the first transgenic mouse expressing an endothelial marker. Poster Presentation: 36th Annual Meetings of the American Pediatric Surgical Association, (APSA) Phoenix, AZ, May 2005.

(Visit PubMed to view this faculty member's most recent articles.)

Columbia University Medical Center
Morgan Stanley Children’s Hospital North Room 215
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New York, NY   10032

Phone: 212-342-8586

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