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Isaac George, MD

Positions and Appointments

2012-present  Attending Surgeon, Heart Valve Center
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2012-present  Assistant Professor of Surgery
Division of Cardiothoracic Surgery, Department of Surgery, New York Presbyterian Hospital/Columbia University Medical Center , New York, NY
2013-present  Surgical Director, Transcatheter Cardiovascular Therapies Director
Hybrid Coronary Interventions, New York, NY

Clinical Specialties

Adult aortic and mitral valve surgery
Transcatheter aortic and mitral valve implantation
Hybrid coronary artery bypass surgery
Complex aortic aneurysm surgery
Complex valvular surgery
Heart failure and transplant surgery
Reoperative cardiac surger
Thoracic aortic endograft implantation

Research Interests

Director, Cardiac Surgery Research Lab

1. Regulation of myostatin signaling in human cardiomyopathy

2. TGFB regulation in non-syndromic aortic aneurysm formation

3. Valve interstitial cell activation mechanisms after surgical and transcatheter valve replacement

4. Clinical outcomes after valve and hybrid surgery

Education and Training

2011-2012  Interventional Cardiology/Hybrid Cardiac Surgery Fellowship
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2011  Ventricular Assist Device/Cardiac Transplant Fellowship, Minimally Invasive, Cardiac Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2009-2011  Fellow, Cardiothoracic Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2008-2009  Post-Doctoral Clinical Fellow, Cardiothoracic Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2006-2008  Resident, General Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2004-2006  Research Fellow, Cardiothoracic Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2002-2004  Resident, General Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
2001-2002  Internship, General Surgery
New York Presbyterian Hospital - Columbia University Medical Center, New York, NY
1997-2001  MD, Medicine
Duke University School of Medicine, Durham, NC
1993-1997  BS, Mechanical Engineering
Massachusetts Institute of Technology, Cambridge, MA

Board Certifications

American Board of Thoracic Surgery, 2012-
American Board of Surgery, 2008-
Certification, Pediatric Advanced Life Support, 2008-
Certification, Advanced Trauma Life Support, 2006-
MD, State of New York, 2005-
Certification, Advanced Cardiac Life Support/Basic Life Support, 2001-
United States Medical Licensing Examination Step 3, 2004
United States Medical Licensing Examination Step 2, 2001
United States Medical Licensing Examination Step 1, 2000

Professional Honors

2008 Blakemore Prize – Best Resident Research Award, Columbia University College of Physicians and Surgeons

2007 Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons

2006 Blakemore Award - Best Resident Research Award, Columbia University College of Physicians and Surgeons

2004 New Era Cardiac Surgery Conference Scholarship

1995 Pi Tau Sigma, Mechanical Engineering Honor Society

1993 Duke University Comprehensive Cancer Center Fellowship

Professional Societies and Committees

2014- Fellow, American College of Cardiology

2013- Member, International Society of Heart and Lung
Transplantation

2012- Member, Society of Thoracic Surgeons

2005-06 American Society of Artificial Internal Organs

2004- Member, American Heart Association

1997-01 Member, American Medical Association

Selected Publications

Invited Presentations:

Coronary Artery Bypass Conduit Choice: "Decision Making and Strategy." Center for Interventional Vascular Therapy Research Meeting, June 22, 2012. New York Presbyterian Hospital – Columbia University Medical Center, New York, NY.

“Acute Myocardial Infarction and Cardiogenic Shock.” CATCH-UP 2012 Annual Meeting: Heart Failure, Devices, and Interventions. May 17, 2012. New York Presbyterian Hospital-Columbia University Medical Center, New York, NY.

“Transcatheter Aortic Valve Replacement.” 10th Annual Innovations in Complex Vascular & Endovascular Interventions, May 11, 2012, New York, NY.

“Intraoperative TEE and Surgical Case Interactive Session: TAVI.” Scientific Sessions of the American Heart Association, November 14, 2011, Orlando, FL.

Moderator – ACC Fellows Session: Advanced Training in Valvular Heart Disease. Transcatheter Cardiovascular Therapeutics Annual Meeting, November 7, 2011, San Francisco, CA.

“Working with Cardiothoracic Surgeons” – ACC Fellows Session: Advanced Training in Valvular Heart Disease. Transcatheter Cardiovascular Therapeutics Annual Meeting, November 7, 2011, San Francisco, CA.

Session Moderator. “Aneurysmal Disease - Innovative Surgical Techniques and Technologies”. Transcatheter Cardiovascular Therapeutics Annual Meeting, November 7, 2011, San Francisco, CA.

“Composite Aortic Root Surgery: Is Anyone Too Young for a Tissue Valve?” Transcatheter Cardiovascular Therapeutics Annual Meeting, November 7, 2011, San Francisco, CA.

Discussant. “Surgical, Interventional, and Hybrid Procedures” Transcatheter Cardiovascular Therapeutics Annual Meeting, November 7, 2011, San Francisco, CA.

“Surgical, Interventional, and Hybrid Procedures: CABG, PCI, Hybrid, or Medical Therapy?” Transcatheter Cardiovascular Therapeutics Annual Meeting, November 7, 2011, San Francisco, CA.

“The Future of TAVI.” Session Moderator, European Association of Cardio-Thoracic Surgery Annual Meeting, October 5th, 2011, Lisbon, Portugal.

“Management of the Pleural Space.” American Association of Thoracic Surgeons – Allied Health Professionals Symposium, Annual Meeting, May 7th, 2011, Philadelphia, PA.

“Aortic Vascular Pathology.” 6th Annual Noninvasive Vascular Laboratory Symposium, Vascular Society of New Jersey, Sept. 28th, 2007, Parsippany, NJ.

“Acute Mesenteric Ischemia.” Columbia University Department of Surgery Grand Rounds. January 4th, 2007.

“The Use of Clenbuterol in Patients Supported with an LVAD.” 4th Annual Mechanical Circulatory Support Symposium. Dec. 9-10th, 2005, Berlin, Germany.

Peer-Reviewed Journal Articles:

Paradis JM, Kodali SK, Hahn RT, George I, Danueault B, Koss E, Nazif T, Leon MB, Williams MR. Concomitant Transcatheter Arotic and Mitral Valve-in-Valve Replacements using Transfemoral Devices via the Trans-Apical Route: First Case in the United States. (submitted)

Hahn R, Paradis JM, Kodali S, Denault B, Koss E, George I, Leon MB, Williams MR. Predicting Paravalvular Regurgitation Following Transcatheter Valve Replacement: Utility of Three-Dimensional Echocardiography Measurements of the Aortic Annulus. (submitted)

Paradis JM, George I, Deneault B, Nazif T, Leon MB, Moses JW, Kodali S, Williams M. Management of Left Main Obstruction after Trans-Apical TAVR in a Patient with Complex Vascular Anatomy. (in preparation).

Denault B, Koss E, Hahn R, Kodali S, Williams MR, Genereux P, Paradis JM, George I, Reiss GR, Moses JW, Smith CR, Leon MB. Efficacy and Safety of Post-Dilatation to Reduce Para-Valvular Regurgitation During Balloon-Expandable Transcatheter Aortic Valve Replacement. (accepted JACC: Interventions)

Zhang X, Ding N, Wang H, Augostini R, Yang B, Xu D, Ju W, Hou X, Li X, Ni B, Cao K, George I, Wang J, Zhang S. Transvenous Phrenic Nerve Stimulation in Patients with Cheyne-Stokes Respiration and Congestive Heart Failure: A Safety and Proof-of-Concept Study. Chest 2012. (accepted-pending publication)

George I, Bish LT, Maybaum S, Naka Y, Chen J, Sweeney HL. Myostatin Regulation in Pediatric Cardiomyopathy. PLoS One 2011;10.1371/journal.pone.0023818.

Russo MJ, Easterwood R, Williams MR, George I, Stewart AS. Aortic Root and Right Ventricular Outflow Tract Reconstruction using Composite Biological Valved Conduits after Failed Ross Procedure. Annals of Thoracic Surgery 2011;91:e87-e89.

George I, Xu K, Wang N, Wang J. β-Adrenergic Receptor Blockade Reduces Endoplasmic Reticulum Stress and Normalizes Calcium Handling in Chronic Heart Failure. Cardiovascular Research 2011;91(3):447-455.

Bish LT, George I. Myostatin serum levels in heart failure. Reply. Eur J Heart Failure 2010;12(12):1379-1380.

George I, Xu K, Klotz S, Xydas S, Zhang G, Cerami A, Wang J. Erythropoeitin Derivate Improves Left Ventricular Systolic Performance and Attenuates Left Ventricular Remodeling in Rats with Myocardial Infarct-Induced Heart Failure. J Cardiovasc Pharm 2010;56(5):506-512.

George I, Xydas S, Klotz SA, Hay I, Chang J, Li Z, Protter AA, Oz MC, Wang J. Long-term Effects of B-Type Natriuretic Peptide Infusion After Acute Myocardial Infarction. J Cardiovasc Pharm 2010;55:14-20.

George I, Bish L, Kamakakkannan G, Oz MC, Naka Y, Sweeney L, Maybaum S. Myostatin Activation in Patients with Advanced Heart Failure and After Mechanical Unloading. Eur J Heart Failure 2010;12:444-453.

George I, Yi GH, Morrow B, Holmes J, Xu EX, Li Z, Protter AA, Oz MC, Wang J. Prolonged Effects of B-Type Natriuretic Peptide Infusion on Cardiac Remodeling After Sustained Myocardial Injury. Am J Phys-Heart Circ Phys 2009;297:H708-H717.

George I, Shah JN, Bacchetta M, Stewart A. Stentless Bioprosthesis in Valved Conduits: Implications for Pulmonary Reconstruction. Ann Thorac Surg 2009;88:2022-2024.

Russo MJ, Davies RR, Hong KN, Chen JM, Argenziano M, Moskowitz A, Ascheim DD, George I, Stewart AS, Williams M, Gelijins A, Naka Y. Matching High-Risk Recipients with Marginal Donor Organs is a Clinically Effective Strategy. Ann Thorac Surg 2009;87:1066-71.

George I, Geddis MS, Lill Z, Lin H, Gomez T, Blank M, Oz MC, Goodman R. Myocardial Function Improved by Electromagnetic Field Induction of Stress Protein hsp70. J Cellular Physiol 2008:216;816-823.

George I, Colley P, Russo M, Martens T, Burke E, MC, Deng MC, Mancini DM, Naka Y. Association of device surface and biomaterials with immunologic sensitization after mechanical support. J Thorac Cardiovasc Surg 2008;135:1372-9.

Kamalakkannan G, Petrilli CM, George I, LaManca J, McLaughlin BT, Shane E, Mancini DM, Maybaum S. Clenbuterol increases lean muscle mass but not endurance in patients with chronic heart failure. J Heart Lung Transplant 2008;27(4):457-61.

George I, Cheng Y, Yi GH, Reiken S, Gu A, Tao YK, Muraskin J, Qin S, He KL, Hay I, Yu K, Oz MC, Holmes J, Burkhoff D, Wang J. Bradycardic Therapy Improves Left Ventricular Function and Remodeling in Dogs with Coronary Embolization-Induced Chronic Heart Failure. J Pharm Exp Therap 2007;321(2):469-76.

Russo MJ, Chen JM, Sorabella RA, Martens TM, Garrido M, Davies RR, George I, Cheema FH, Mosca RS, Mital S, Ascheim DD, Argenziano M, Stewart AS, Oz MC, Naka Y. Effect of ischemic time on survival following heart transplantation varies by donor age: an analysis of the United Network of Organ Sharing Database. J Thorac Cardiovasc Surg 2007;133:554-9.

George I, Xydas S, Mancini DM, Lamanca J, DiTullio M, Marboe CC, Shane E, Schulman AR, Colley PM, Petrilli CM, Naka Y, Oz MC, Maybaum S. Effect of Clenbuterol on Cardiac and Skeletal Muscle Function with Ventricular Assist Device Support. J Heart Lung Transplant 2006;25:1084-90.

George I, Xydas S, Topkara VK, Ferdinando C, Barnwell EC, Gableman L, Sladen R, Naka Y, Oz MC. Clinical Indication for Use and Outcomes After Inhaled Nitric Oxide. Annals of Thoracic Surgery 2006;82:2161-2169.

Russo MJ, Davies RR, Sorabella RA, Martens TM, George I, Cheema FH, Mital S, Mosca RS, Chen JM. Adult-age donors offer acceptable long-term survival to pediatric heart transplant recipients: an analysis of the United Network of Organ Sharing Database. J Thorac Cardiovasc Surg 2006;132(5):1208-12.

Bardakci H, Cheema FH, Topkara VK, Dang NC, Martens TP, Mercando ML, Forster CS, George I, Russo MJ, Oz MC, Esrig BC. Discharge-to-Home Rates in Octogenarians Are Significantly Lower in Coronary Artery Bypass Grafting Patients. Ann Thorac Surg 2007;83:483-489.

George I, Yi GH, Schulman AR, Morrow BT, Cheng Y, Gu A, Zhang G, Oz MC, Burkhoff D, Wang J. A Polymerized Bovine Hemoglobin Oxygen Carrier Preserves Regional Myocardial Function and Reduces Infarct Size after Acute Myocardial Ischemia. Am J Physiol – Heart Circ Phys 2006;291:H1126-H1137.

George I, Cheng Y, Yi GH, He KL, Li X, Oz MC, Holmes J, Wang J. Effect of Passive Cardiac Containment on Ventricular Synchrony and Cardiac Function in Awake Dogs. Euro J Cardiothorac Surg 2007;31:55-64.

George I, Yi GH, He KL, Lee MJ, Calahan P, Zhang G, Gu A, Klotz S, Burkhoff DB, Wang J. Direct Left Ventricle to Coronary Artery Stent Restores Perfusion to Ischemic Swine Myocardium. Heart Surgery Forum 2006;9(5):E744-9.

Topkara VK, Dang NC, Barili F, Martens TP, George I, Cheema FH, Bardacki H, Ozcan AV, Naka Y. Ventricular Assist Device use for the treatment of acute viral myocarditis. J Thorac Cardiovasc Surg 2006;131(5):1190-1.

Topkara VK, Dang NC, Barili F, Cheema FH, Martens TP, George I, Bardakci H, Oz MC, Naka Y. Predictors and outcomes of continuous venovenous hemodialysis use after left ventricular assist device implantation. J Heart Lung Transplant 2006;25(4):404-8.

George I, Hardy MA, Widmann WD. John Benjamin Murphy. Current Surgery 2004;61(5):439-41.

Book Contributions:

George I, Williams MR. Transapical AVR – Valve in valve for a prior AV Bioprosthesis. Cardiac Surgical Techniques (1st Edition). Franco K, Roselli E, Slaughter M, Thourani V, 2013.

George I, Reis GR, Williams MR. Transcatheter Aortic Valve Replacement. Mastery of Cardiothoracic Surgery, 3rd Edition. (pending publication)

George I, Williams MR. Myocardial Revascularization after Acute Myocardial Infarction. Cardiac Surgery in the Adult (4th Edition). Cohn LH, Edmunds LH Jr. The McGraw-Hill Companies, Inc., 2011.

George I, Oz MC. Myocardial Revascularization after Acute Myocardial Infarction. Cardiac Surgery in the Adult (3rd Edition). Cohn LH, Edmunds LH Jr. The McGraw-Hill Companies, Inc., 2007.

Abstracts:

Genereux P, Green P, Kodali S, Williams MR, Denault B, Reiss GR, Paradis JM, George I, Kirtane A, Woglom A, Hahn RT, Moses JW, Smith CR, Leon MB. Incidence and Impact of Acquired Thrombocytopenia on Bleeding events and Mortality after Transcatheter Aortic Valve Replacement (TAVR): Experience from Columbia University Medical Center.American College of Cardiology, Annual Meeting 2012.

Hahn R, Paradis JM, Kodali S, Denault B, Koss E, George I, Leon MB, Williams MR. Predicting Paravalvular Regurgitation Following Transcatheter Valve Replacement: Utility of Three-Dimensional Echocardiography Measurements of the Aortic Annulus. Transcatheter Technology Annual Meeting, Miami, FL, 2012.

Genereux P, Green P, Kodali S, Williams MR, Denault B, Reiss GR, Paradis JM, George I, Kirtane A, Woglom A, Hahn RT, Moses JW, Smith CR, Leon MB. Incidence and Impact of Acute Kidney Injury post Trans-catheter Aortic Valve Replacement using the new Valve Academic Research Consortium Cirteria. American College of Cardiology, Annual Meeting 2012.

George I, Bish LT, Maybaum S, Naka Y, Sweeney HL, Chen JM. Myostatin Expression is Markedly Increased after Biventricular Mechanical Support in Congenital Heart Disease.Scientific Sessions of the American Heart Association, Chicago, IL 2010.

Nassem T, Scripps T, Liu SC, Gin G, George I, Geddis MS, Oz MC, Goodman R. Noninvasive Exposure to Electromagnetic Fields Improved Cardiac Function and Survival in Rodent Model.New Era Cardiac Care Annual Conference, San Diego, CA, 2008.

Goodman R, Pak SW, Lin-Ye A, Liu YF, Scripps T, Geddis MS, George I. A Noninvasive Technique For Preserving Myocardial Function After Ischemia-Reperfusion. Bioelectromagnetic Society Annual Meeting, San Diego, CA, 2008.

Russo M, Chen JM, Hong KN, Argenziano M, Davies RR, George I, Ascheim DD, Moskowitz A, Geljins A, Oz MC, Naka Y. Alternate Listing Transplantation is a Cost-Effective Treatment for End-Stage Heart Failure Patients.Scientific Sessions of the American Heart Association, Orlando, FL 2007.

Russo M, Chen JM, Hong KN,Argenziano M, Davies RR, Martens T, George I, Stewart A, Geljins A, Moskowitz A, Oz MC, Naka Y. Transplanting High-risk Recipients with Marginal Donor Hearts is Clinically Effective. Scientific Sessions of the American Heart Association, Orlando, FL 2007.

Bish L, George I, Colley P, Petrilli C, Oz MC, Sweeney L, Maybaum S. Myostatin Activation is Increased in Patients With Congestive Heart Failure and After Mechanical Unloading.Heart Failure Society of America, Washington D.C, 2007.

Martens TP, Russo MJ, George I, Cheema FH, Naseem T, Boswick JA, Topkara VK, Stewart AS, Oz MC, Naka Y. Axial Flow LVADs are Associated with Fewer Device-Related Infections than Pulsatile LVADs. Scientific Sessions of the American Heart Association, Chicago, IL, 2006.

Bish L, George I, Colley P, Petrilli C, Oz MC, Sweeney L, Maybaum S. Myostatin Regulation in Patients with Advanced Heart Failure and After Mechanical Unloading. Circulation 2006;114(18):II-959.Scientific Sessions of the American Heart Association, Chicago, IL, 2006.

Hong KN, Russo MJ, Williams MR, Sorabella R, Martens T, George I, Smith CR, Oz MC, Argenziano M. Surgical Atrial Fibrillation Ablation Risk Score: Using Patient Specific Characteristics to Predict Treatment Success in Persistent AF. Society of Thoracic Surgeons 43rd Annual Meeting, San Diego, CA, 2007.

Hong KN, Russo MJ, Williams MR, Abbasi A, Sorabella R, Martens T, Cheema F, George I, Smith CR, Oz MC, Argenziano M. Patient Specific Characteristics Determine Success of Surgical Atrial Fibrillation Ablation in Patients with Persistent Atrial Fibrillation. Heart Rhythm Annual Meeting 2006.

Goodman R, Geddis M, Lin H, Oz M, George I. Electromagnetic Field Exposures Induce MAP-Kinase and ELK1 Mediated HSP70 Synthesis: Preservation of Myocardial Function After Ischemia-Reperfusion. 4th International Workshop on Biological Effects of Electromagnetic Fields, Crete, Greece, 2006.

Martens TP, Russo MJ, Cheema FH, George I, Tabaksblat MY, Alison-Mayne S, Goldberg JB, Wang R, Bailey SH, Argenziano M, Stewart AS, Mancini DM, Naka Y. Tight Perioperative Glucose Control Is Associated With Fewer LVAD Related Infections And Better Post-VAD Survival. JHLT 2006;25(2S):S80. International Society of Heart and Lung Transplantation Annual Meeting, Madrid, Spain, 2006.

Cheema F, Aggarwal S, Forster CS, Martens TP, Topkara VK, George I, Russo M, Bailey SH, Paultre F, Esrig BC, Oz MC, Mancini DM, Deng MC, Naka Y. UNOS Status at the Time of Heart Transplantation Predicts Long-Term Survival. JHLT 2006;25(2S):S44. International Society of Heart and Lung Transplantation Annual Meeting, Madrid, Spain, 2006.

George I, Colley P, Burke E, Martens T, Morrow B, Russo M, Soneru C, Tabaksblat M, Spadaccio C, Lill Z, Cheema F, Itescu S, Deng M, Mancini D, Oz MC, Naka Y. Sensitization in Axial Flow Devices Versus Pulsatile Left Ventricular Assist Devices. JHLT 2006;25(2S):S145. International Society of Heart and Lung Transplantation Annual Meeting, Madrid, Spain, 2006.

George I, Xydas S, Lamanca J, Colley P, Petrilli C, Mancini D, DiTullio M, Marboe C, Shane E, Naka Y, Oz M, Maybaum S. Effect of Clenbuterol on Cardiac and Skeletal Muscle Function during LVAD Support. JHLT 2006;25(2S);S125. International Society of Heart and Lung Transplantation Annual Meeting, 2006, Madrid, Spain.

George I, Cheng Y, Yi GH, Morrow B, Muraskin J, Soneru C, Oz MC, Protter AA, Li Z, Wang J. Continuous Brain Natriuretic Peptide Infusion Preserves Systolic Function after Myocardial Ischemia and Prevents Ventricular Remodeling in Conscious Dogs. J Am Coll Cardiol 2006;47(4) Suppl A:89A. American College of Cardiology Annual Meeting, Atlanta, GA, March, 2006.

Williams MR, Russo MJ, Hong KN, Topkara VK, Laitman AP, Cheema FH, Martens TP, George I, Smith CR, Oz MC, Argenziano M. Surgical Atrial Fibrillation Ablation using laser energy is safe and effective. Abstracts, Course Syllabus for the 9th Annual New Era Cardiac Care: Innovation & Technology.New Era Cardiac Care Annual Conference, Newport Beach, CA, 2006.

Topkara VK, Russo MR, Williams M, Liu J, Liang L, Barili M, Martens TP, Cheema FC, George I, Oz MC, Smith CR, Argenziano M. Increased Left Atrial Size Is Associated with Increased Rhythm Failure and Postoperative Stroke Following Surgical Atrial Fibrillation Ablation. Abstracts, Course Syllabus for the 9th Annual New Era Cardiac Care: Innovation & Technology. New Era Cardiac Care Annual Conference, Newport Beach, CA, 2006.

Williams M, Russo MJ, Topkara VK, Hong K, Martens TP, Cheema FC, George I, Smith CR, Oz MC, Argenziano M. Early Clinical Experience with Surgical Atrial Fibrillation Ablation using Laser Energy. Abstracts, Course Syllabus for the 9th Annual New Era Cardiac Care: Innovation & Technology.New Era Cardiac Care Annual Conference, Newport Beach, CA, 2006.

Topkara VK, Cheema FH, Martens T, George I, Russo MJ, Cheema AF, Barili F, Forster CS, Oz MC, Esrig BC. Coronary Artery Bypass Grafting In Patients With Peripheral Vascular Disease Conveys Larger Risk In A Multicenter Regional Database. Abstracts, Course Syllabus for the 9th Annual New Era Cardiac Care: Innovation & Technology. New Era Cardiac Care Annual Conference, Newport Beach, CA, 2006.

George I, Colley P, Chen S, Lill Z, Xydas S, Vaseilescu ER, Morrow B, Martens T, Russo M, Cheema F, Burke E, Naka Y, Suciu-Foca N, Stewart A, Oz MC, Itescu S. Serum CD40 Ligand and CD28 Levels Do Not Predict Immunologic Status after Cardiac Transplantation. Abstracts, Course Syllabus for the 9th Annual New Era Cardiac Care: Innovation & Technology.New Era Cardiac Care Annual Conference, Newport Beach, CA, January, 2006.

Bardacki H, Cheema FH, Topkara VK, Dang NC, Martens TP, Mercando ML, Forster CS, Benson AA, George I, Russo MJ, Oz MC, Esrig BC. Discharge-to-Home Rate is Significantly Lower in Octogenarians Undergoing Coronary Artery Bypass Grafting: Results From An Audited State-Wide Mandatory Database. Annals Thorac Surg 2007;83:483-9. Society of Thoracic Surgeons Annual Meeting, Chicago, IL, January, 2006.

Cheema FC, Martens TP, Duong JK, Topkara VK, Elhosseiny RA, George I, Russo MR, Forster CS, Weinberg AD, Argenziano M, Oz MC, Esrig BC. Comparison of Minimally Invasive Versus Standard Approach to Mitral Valve Surgery: Results from an Audited State-Wide Mandatory Database. Society of Thoracic Surgeons Annual Meeting, Chicago, IL, January, 2006.

George I, Lill Z, Geddis MS, Lin H, Xydas S, Ippagunta N, Goodman R. Electromagnetic Field Radiation Induces MAP-Kinase and ELK1 Mediated hsp70 Synthesis and Preserves Myocardial Function After Ischemia-Reperfusion. Circulation 2005;Suppl 112(17):II-196. Scientific Sessions of the American Heart Association, Dallas, TX, 2005.

George I, Xydas S, Lamanca J, Schulman A, Mancini D, DiTullio M, Marboe C, Shane E, Petrilli C, Naka Y, Oz MC, Maybaum S. Clenbuterol Improves Skeletal Muscle Strength But Not Cardiac Function in Patients Supported with a Left Ventricular Assist Device. Circulation 2005;Suppl 112(17):II-337. Scientific Sessions of the American Heart Association, Dallas, TX, 2005.

Cheema FH, Topkara VT, Beg S, Martens TP, George I, Colman DL, Forster CS, Mangi AA, Oz MC, Esrig BC. The Effect of Low Left Ventricular Ejection Fraction on Patients Undergoing Isolated Mitral Valve Surgery: Early Results from a State-Wide Mandatory Database. Circulation 2005;Suppl 112(17):II-495. Scientific Sessions of the American Heart Association, November, Dallas, TX, 2005.

George I, Yi G, Schulman, Cheng Y, Gu A, Zhang G, Oz MC, Burkhoff D, Wang J. HBOC-201 Preserves Regional Myocardial Function and Perfusion in an Acute Ischemia Dog Model. International Symposium on Blood Substitutes, Providence, RI, June, 2005.

Dang NC, Topkara VK, Ferber P, George I, Burkhoff DB, Oz MC, Naka Y, Dickstein ML. Transvalvular Intra-aortic Ventricular Assist Device Achieves Functional Cardiac Improvement in Computer Heart Failure Model. ASAIO Journal 2005;51(2):24A.American Society of Artificial Internal Organs Annual Meeting, Washington, DC, 2005.

Dang NC, Topkara VK, Kim BT, Mercando ML, Kay J, Martens TP, George I, Cheema FH, Oz MC, Naka Y. Advanced Age, Female Gender, Diabetes Mellitus, and Preoperative Malnutrition Predict Poor Outcome in Patients with Chronic Congestive Heart Failure Who Undergo Left Ventricular Assist Device Implantation. American Association for Thoracic Surgery Annual Meeting, San Francisco, CA, April, 2005.

Topkara VK, Dang NC, Martens TP, Cheema FH, George I, Oz MC, Naka Y. Diabetes Reduces Long-Term Post-Transplant Survival in Left Ventricular Assist Device Patients. J Am Coll Cardiol 2005;45(3)Suppl:132A. American College of Cardiology Annual Meeting, Orlando, FL, March, 2005.

Bardakci H, Topkara VK, Cheema FH, Dang NC, Martens TP, George I,Kesavaramanujam S, Namerow PB, Oz MC, Landry DW. Outcomes After Coronary Artery Bypass Grafting in Non-Dialysis Dependent Renal Failure Patients. J Am Coll Cardiol 2005;45(3)Suppl:223 A. American College of Cardiology Annual Meeting, Orlando, FL, March, 2005.

Dang NC, Mercando ML, Kay J, Topkara VK, Kruger KH, Aboodi MS, Martens TP, George I, Cheema FH, Oz MC, Naka Y. Right Heart Failure Following Left Ventricular Assist Device Implantation in Patients with Chronic Congestive Heart Failure. JHLT 2005;24(2):S147. International Society of Heart and Lung Transplantation Annual Meeting, Philadelphia, PA, 2005.

Topkara VK, Williams MR, Dang NC, Lieberman E, Liu JF, Cheema FC, Martens TP, George I, Oz MC, Argenziano M. Impact of Different Energy Sources on Surgical Ablation of Atrial Fibrillation: A Comparative Analysis. Abstracts, Course Syllabus for the 8th Annual New Era Cardiac Care: Innovation & Technology, p.53-4.New Era Cardiac Care Annual Conference, Dana Point, CA, January, 2005.

Dang NC, Kruger KH, Mercando ML, Kay J, Martens TP, George I, Topkara VK, Cheema FH, Stewart AP, Oz MC. Mitral Valve Artificial Chord Placement: A Percutaneous Approach. Abstracts, Course Syllabus for the 8th Annual New Era Cardiac Care: Innovation & Technology, p.55-6. New Era Cardiac Care Annual Conference, Dana Point, CA, January, 2005.

Martens TP, George I, Oz MC. A Method for Increasing the Ferromagnetic Properties of Blood. New Era Cardiac Care Annual Conference, Dana Point, CA, January 2005.

George I, Yi GH, Schulman A, Gu A, Cheng Y, Zhang G, Oz MC, Wang J. The Effects of HBOC-201 on Regional Myocardial Function and Recovery in an Acute Ischemia Model. Abstracts, Course Syllabus for the 8th Annual New Era Cardiac Care: Innovation & Technology, p.55-6.New Era Cardiac Care Annual Conference, Dana Point, CA, January, 2005.

George I, Williams M. The Device for Optimization of Cardiac Function. Abstracts, Course Syllabus for the 8th Annual New Era Cardiac Care: Innovation & Technology, p.55-6.New Era Cardiac Care Annual Conference, Dana Point, CA, January 2005.

George I, Xydas S, Topkara V, Ferrandino CC, Gableman L, Barnwell E, Cheema FH, Dang NC, Martens TP, Schulman A, Naka Y, Oz MC. The Long-Term Survival, Cost, and Quality of Life Associated with Inhaled Nitric Oxide Therapy. Abstracts, Course Syllabus for the 8th Annual New Era Cardiac Care: Innovation & Technology, p.55-6. New Era Cardiac Care Annual Conference, Dana Point, CA, January 2005.

George I, Assar M, Wolf PD, von Ramm OT. Non-Invasive Measurement of Central Pulse Pressure using Real-Time 3-Dimensional Echocardiography. Circulation 2000;102(18):II-723. Scientific Sessions of the American Heart Association, New Orleans, LA, 2000.

Non-Print Media:

Discussion of Dick Cheney Heart Transplant - http://abclocal.go.com/wabc/video?id=8594336

George I. “Acute Mesenteric Ischemia.” www.clinicaltrialresults.org, 2007.

(Visit PubMed to view this faculty member's most recent articles.)






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