James V. Guarrera, MD - Department of Surgery

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James V. Guarrera, MD

Positions and Appointments
2006-present		Assistant Professor of Surgery
2006-present		Columbia University College of Physicians and Surgeons, New York, NY
2006-present		Attending Surgeon
2006-present		NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2008-present		Surgical Director, Adult Liver Transplantation
2008-present		NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY

Clinical Specialties

Liver Transplantation
Hepatobiliary Surgery
Renal Transplantation
Pancreas Transplantation
Minimally Invasive Solid Organ Surgery

Research Interests

Organ preservation
Ischemia/Reperfusion Injury
Hepatocellular Carcinoma
Liver Regeneration

Visit the Molecular Therapies and Organ Preservation lab.

Education and Training
2004-2006		Liver/Renal Transplantation Fellowship and Hepatobiliary Surgery
2004-2006		NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2004		Renal/Pancreas Transplantation Fellowship
2004		Weill Cornell Medical College, New York, NY
2004		ASTS Multi-Organ Transplant Fellowship
2004		NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2003-2004		Chief Resident
2003-2004		NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1998-2003		General Surgery Resident
1998-2003		NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
1998		MD
1998		Mount Sinai School Of Medicine, New York, NY
1994		BA, Biology, minor in Chemistry
1994		Hofstra University, Hempstead, NY

Board Certifications

New York State Medical License, 1999-present

DEA Certificate, 2004-2007

Diplomate, American Board of Surgery, 2005-present

American Society of Transplant Surgeons Certification
2006-present

New Jersey State Medical License 2007-present

United Network for Organ Sharing: Primary Live Donor
Liver Transplant Surgeon Certification 2007-present

Professional Experience

2003-present		Director of Liver Preservation
2003-present		Center for Liver Disease and Transplantation, Department of Surgery, New York Presbyterian Hospital, New York, NY
2001-2002		Gross Anatomy Lab Preceptor, Medical School Gross Anatomy
2001-2002		College Of Physicians And Surgeons, Columbia University, New York, NY
2001-2002		Course Lecturer, Third Year Surgery Clerkship:
2001-2002		College Of Physicians And Surgeons, Columbia University, New York, NY
2001-2002		Course Director, Third Year Medical Student Suturing
2001-2002		College Of Physicians And Surgeons, Columbia University, New York, NY
2001-2002		Research Fellow, Transplantation and Hepatobiliary Surgery
2001-2002		Center for Liver Disease and Transplantation, Department of Surgery, New York Presbyterian Hospital, New York, NY
1994-1998		Research & Surgical Assistant, Supported Summer Fellowships
1994-1998		The Recanati/Miller Transplantation Institute, The Mount Sinai Medical Center, New York, NY

Professional Honors

Hofstra University:
Dean's List, 1991-1994
Departmental Honors in Biology, Alpha Epsilon Delta, National Premedical Honor Society, 1992
Beta Beta Beta, National Biology Honor Society, 1992

Mount Sinai School Of Medicine:
Alpha Omega Alpha, Honor Medical Society Lambda chapter, inducted, 1997
Arthur Aufses Senior Prize in Surgery, 1998
(Best student performance in Surgery Rotations)

New York Presbyterian Hospital/Columbia University Medical Center:
Internation Liver Transplantation Society, 2006

Award Winner-"Rising Star Symposium" International Liver Transplantation Society Meeting, Milan, Italy May 2006

American Transplant Congress, Young Investigator Award, 2004

The Transplantation Society Young Investigator
Travel Grant, 2002

Blakemore Award for Surgical Research, 2002

Outstanding Resident Teaching Award, 2002

Professional Societies and Committees

Alpha Omega Alpha, Honor Medical Society
American College of Surgeons (Candidate)
American Society of Transplantation
Association for Academic Surgery
International Society for Organ Preservation
The Transplantation Society
Board of Directors, New York Center for Liver Transplantation, Inc.
American Society of Transplant Surgeons

Selected Publications

Guarrera JV, Karim N. Liver Preservation: Is there anything new yet? Curr Opin Organ Transplant 13(2):148-154, April 2008.

Lo IJ, Lefkowitch JH, Feirt N, Alkofer B, Kin C, Samstein B, Guarrera JV, Renz JF. Utility of liver allograft biopsy obtained at procurement. Liver Transpant 2008; 14: Mar 6.

Guarrera JV, Alkofer B, Feirt N, Sandoval R, Samstein B, Smith E, Marshman D, Cogswell C, Vannatta J, Emond JC, Renz JF. Discovery of diffuse biliary microhamartomas during liver procurement. Liver Transplant 2007; 13(10):1470-1.

Fischer JC, Guarrera JV. Modified thoracentesis technique using a triple lumen catheter. Am J Surg 2007; 194: 406-408.

Guarrera JV, Nasr SH, Balachandran V, Reverte C, Samstein B, Brown T, Samuels MJ, Markowitz G, D'Agati V, Ratner LE. Microscopic intrarenal particles after pulsatile machine preservation do not adversely affect outcomes after renal transplantation. Transplant Proc 2006; 38(10):3384-3387.

Alkofer B, Samstein B, Guarrera JV, Kin C, Jan D, Bellemare S, Kinkhabwala M, Brown RS, Emond JE, Renz JF. Extended Criteria Donor Liver Allografts. Semin in Liver Dis 2006; 26(3): 221-233.

Guarrera JV, Estevez J Boykin J, Rashid J Sun S, Arrington B. Hypothermic machine perfusion of liver grafts for transplantation: Technical development in human discard and miniature swine models. Transplantation Proceedings 2005; 37: 323-5.

Guarrera JV, Sinha P, Lobritto SJ, Brown RS, Kinkhabwala M, Emond JC. Microvascular hepatic artery anastomosis in pediatric segmental liver transplantation: Microscope vs. loupe. Transplant International 2004; 17: 585-588.

Russo MW, Brown RS, Lapointe-Rudow D, Teixera A, Guarrera JV, Gaglio P, Emond JC, Kinkhabwala M. Liver function following donor right hepatectomy: Patterns of recovery and implications for management. J Clin Gastroenterol. 2004; 38(9):810-4.

Guarrera JV, Polyak M, Arrington B, Boykin J, Brown T, Jean-Jacques M, Kapur S, Stubenbord WT, Kinkhabwala M. Pushing the envelope in renal preservation: Improved results with novel perfusate modifications for pulsatile machine perfusion of cadaver kidneys. Transplantation Proceedings 2004; 36, 1257–1260.

Zeng S, Feirt N, Goldstein M, Guarrera JV, Ippagunta N, Ekong U, Dun H, Lu Y, Qu W, Schmidt AM, Emond JC. Blockade of receptor for advanced glycation end product (RAGE) attenuates ischemia and reperfusion injury to the liver in mice. Hepatology 2004; 39(2):422- 432.

Kinkhabwala MM, Guarrera JV, Leno R, Brown RS, Prowda J, Kapur S, Emond JC. Outflow reconstruction in right hepatic live donor liver transplantation. Surgery 2003; 133(3): 243-250.

Guarrera JV, Emond JC. Advances in segmental liver transplantation: Can we solve the donor shortage? Transplantation Proceedings 2001; 33(7,8):3451-3455.

Sheiner PA, Magliocca JF, Bodian C, Schluger LK, Altaca G, Guarrera JV, Emre S, Fishbein TM, Guy SR, Schwartz ME, Miller CM. Long-term medical complications in patients surviving> 5 years after liver transplant. Transplantation 2000; 69(5):781-789.

Reich DJ, Fiel I, Guarrera JV, Emre S, Guy SR, Schwartz ME, Miller CM, Sheiner PA. Liver transplantation for autoimmune hepatitis. Hepatology 2000; 32:693-700.

Facciuto M, Heidt D, Guarrera JV, Bodian C, Miller CM, Emre S, Guy SR, Fishbein TM, Schwartz ME, Sheiner PA. Retransplantation for late liver graft failure: predictors of mortality. Liver Transplantation 2000; 6(2):174-179.

Guarrera JV, Hardy MA. William Stewart Halstead: A giant of american surgery. Current Surgery 2000; 57:145-147.

Roayaie S, Guarrera JV, Ye M, Thung SN, Emre S, Fishbein T, Guy S, Sheiner P, Miller CM, Schwartz ME. Aggressive surgical treatment of intrahepatic cholangiocarcinoma: Predictors of outcome. Journal of the American College of Surgeons 1998; 187: 365-372.

Sheiner PA, Guarrera JV, Grunstein E, Emre S, Guy SR, Schwartz ME, Miller CM, Boros P. Increased risk of early rejection correlates with recovery of CD3 count after liver transplant in patients receiving OKT3 induction. Transplantation 1997; 64(8):1214-1216.

Sheiner PA, Varma CVR, Guarrera JV, Garratti M, Emre S, Guy SR, Cooper J, Schwartz ME, Miller CM. Selective revascularization of hepatic artery thrombosis after liver transplant improves patient and graft survival. Transplantation 1997; 64(9):1295-1299.

Schluger LK, Sheiner PA, Jonas M, Guarrera JV, Fiel I, Meyers B, Berk PD. Isoniazid hepatotoxicity after orthotopic liver transplantation. The Mount Sinai Journal of Medicine 1996; 63(5&6):364-369.

Pelcovitz D, Kaplan S, Goldenberg B, Mandel F, Lehane J, Guarrera JV. Post-traumatic stress disorder in physically abused adolescents. Journal of the American Academy of Child and Adolescent Psychiatry 1994; 33(3):305-312.

Selected Presentations and Abstracts

Guarrera JV,Samstein B, Kin CJ, Kinkhabwala M, Jan D, Dove L, Gaglio P, Lobritto S, Brown RS, Emond JC, Renz JF. Utilization of Expanded Criteria Donor Liver Allografts: Who and When? Accepted at May 2006 International Liver Transplantation Society Meeting, Milan, Italy. Award Winner-"Rising Star Symposium" Oral Presentation.

Samstein B, Guarrera JV, Kin CJ, Emond JC, Renz JF. Early Experience Utilizing Bevacizumab as Neoadjuvant and Adjuvant of Hepatocellular Carcinoma That Exceed Current Transplant Criteria (Accepted at May 2006 International Liver Transplantation Society Meeting, Milan, Italy.

Reverte C, Guarrera JV, Renz JF, Samstein B, Jan D, Kinkhabwala M, Emond JC. Liver Transplantation for Hepatocellular Carcinoma: Outcomes of live donor versus cadaveric transplants. For Oral presentation at American Hepatopancreaticobiliary Association annual meeting, Miami, FL, March 2006. J Gastrointest Surg 2006.

Guarrera JV, Reverte C, Renz JF, Samstein B, Jan D, Kinkhabwala M, Emond JC. Systematic Use Of Live Donor Liver Transplantation: Differential Impact On Children And Adults. To be presented as a Poster of Distinction, American Hepatopancreaticobiliary Association annual meeting, Miami, FL, March 2006. J Gastrointest Surg 2006.

Samstein B, Kin C, Goldstein MG, Guarrera JV, Renz JF, Emond JE. Parenchymally Challenged Donors with Equivalent Outcomes to Standard Donor Grafts or Living Donor Grafts. Poster Presentation, The 55th annual meeting of The American Association for the Study of Liver Disease, San Francisco, CA, November, 2005. Hepatology 2005 Supplement.

Goldstein MJ, Lee S, Guarrera JV, Cohen DJ, Hardy MA, .Rituximab rescue for refractory antibody mediated rejection after kidney transplantation. Oral Presentation, American Transplantation Congress Seattle, WA, May 2005. Transplantation 2005; 79: 949.

Guarrera JV, Arrington B, Estevez J, Boykin J, Kapur S, Emond JC, Stubenbord WT, Kinkhabwala M.Liver Preservation with Vasosol Solution: A single center comparison with U.W. Solution. Poster Presentation, 20th International Congress of the Transplantation Society, Vienna, Austria, September 2004. Transplantation 2004; 78(2): 206.

Guarrera JV, Arrington B, Estevez, R Boyce R, Rashid J, Kapur S, Emond JC, Stubenbord WT, Kinkhabwala M. Hypothermic Machine Perfusion of Liver Grafts For Transplantation: Assessment and Development In Human Discard and Miniature Swine Models. Oral Presentation, 20th International Congress of the Transplantation Society, Vienna, Austria, September 2004. Transplantation 2004; 78(2): 201.

*Guarrera JV, Polyak M, Arrington B, Emond JC, Stubenbord WT, Emond JC, Kinkhabwala M. Normothermic preservation with a novel machine perfusate reduces ischemia/reperfusion injury in a porcine liver model. Oral Presentation, American Transplant Congress, Transplant 2004, Boston, MA, May 2004. Young Investigator Award Winner; American J Transplant 2004; 4 (supl 8): 254.

Guarrera JV, Polyak M, Arrington B, Estevez J, Stubenbord WT, Emond JC, Kinkhabwala M. Hypothermic Machine Perfusion of Liver Grafts For Transplantation: Preclinical Assesment In Human Discard And Miniature Swine Models. Oral Presentation, American Transplant Congress, Transplant 2004, Boston, MA May 2004. American J Transplant 2004; 4 (supl 8): 571.

Susman J, Haskal ZJ, Foley IH, Weintraub JL, Rundback JH, Guarrera JV, et al. Efficacy of percutaneous dilation of anastamotic biliary strictures in living-donor liver transplant recipients. Oral Presentation at SCVIR annual meeting. JVIR 2003; 2(part2): S14;.

Lantis J, Ude A, Guarrera JV. Laparoscopic control of type 1 endoleaks in a novel porcine model. Oral presentation, International Endvascular and Laparoscopic Congress, Quebec, Canada, May 2003.

Kinkhabwala M, Ryan LP, Guarrera JV, Kapur S, Marvin MR, Emond JC. Improving operative efficiency in right hepatic live donor liver transplantation. Poster Presentation, American Transplant Congress, Transplant 2002, Washington, D.C., April 2002. American J Transplant 2002; 2(supl 3): 302.

Marvin MR, Sinha P, Guarrera JV, Donovan M, Emond JC. Clinician directed selection of the optimal transplant recipient, failure of the UNOS 2A criteria. Poster Presentation, American Transplant Congress, Transplant 2002, Washington, D.C., April 2002. American J Transplant 2002; 2(sup1 3): 300.

Guarrera JV, Sinha P, Marvin MR, Kapur S, Kinkhabwala, M, Lobritto SJ, Emond JC. Microvascular hepatic artery anastomosis in pediatric segmental liver transplantation: Microscope vs. loupe. Poster presentation, The Biennial Meeting of The International Association for the Study of the Liver, Madrid, Spain, April 2002. J of Hepatology 2002; 36(supl 1): 188.

Guarrera JV, Polyak MMR, Arrington B, Kapur S, Kinkhabwala M, Stubenbord WT. Oxygenated Warm Perfusion With a Novel Solution Reduces Ischemia/Reperfusion Injury In A Porcine Liver Model. Oral Presentation, Advances in Organ Transplantation, 2002 Fellows’ Conference, Irving, TX, March 2002.

Kinkhabwala M, Goldstein M, Sussman J, Kapur S, Guarrera JV, Weintraub J, Haskal Z, Emond JC. Complex biliary reconstructions in adult-to-adult living-donor liver transplantation are feasible and expand the donor pool. Oral Presentation, American Association for the Study of Liver Diseases, Dallas, TX, November 2001. Hepatology 2001; 34(4) pt 2: 245A.

Goldstein M, Guarrera JV, Marvin MR, Cataldegirmen G, Kapur S, Kinkhabwala M, Brown R, Emond JC. Comparative analysis of biliary complications in adults and children after living-donor liver transplant. Poster presentation, American Association for the Study of Liver Diseases, Dallas, TX, November 2001. Hepatology 2001; 34(4) pt 2.

Schluger LK, Ferran E, Ye M, Guarrera JV, Bodenheimer HC, Sheiner PA. Liver graft loss from recurrent autoimmune hepatitis. Poster presentation, American Association for the Study of Liver Diseases section of the Digestive Diseases Week, New Orleans, LA, May 1998. Gastroenterology 1998; 114(4) pt 2: A1336-A1337 (L0568).

Guarrera JV, Guine T, Varma SC, Boros P, Miller CM, Sheiner PA. Recovery of CD3 counts by ten days after liver transplant in patients receiving OKT3 induction correlates with increased risk of early rejection. Poster presentation, Mount Sinai School of Medicine Research Day, New York, NY, March 1996.

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