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Mathew R. Williams, MD

Positions and Appointments

2011-present  Co-Director, Heart Valve Center
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2007-present  Assistant Professor of Surgery (in Medicine)
Columbia University College of Physicians and Surgeons, New York, NY
2007-present  Surgical Director, Cardiovascular Transcatheter Therapies
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY
2010-present  Associate Director, Cardiothoracic Fellowship
NewYork Presbyterian Hospital/Columbia University Medical Center, New York, NY
2007-present  Attending Surgeon and Interventional Cardiologist
NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY

Clinical Specialties

Percutaneous and catheter based therapy for valvular heart disease

Percutaneous treatment of coronary artery disease

Percutaneous treatment of aortic aneurysm disease

Percutaneous ventricular assist devices
Minimally invasive heart surgery

Surgical Treatment of atrial fibrillation

Combined Surgical and Interventional Procedures

Research Interests

Percutaneous Valve Therapy

Hybrid cardiac procedures

Surgical Treatment of Atrial Fibrillation


Education and Training

2006  Fellowship, Interventional Cardiology
New York Presbyterian Hospital/Columbia University Medical Center, New York, NY
2004-2005  Fellowship, Cardiothoracic Surgery
New York Presbyterian Hospital/Columbia University Medical Center, New York, NY
2001-2003  Residency, General Surgery
New York Presbyterian Hospital/Columbia University Medical Center, New York, NY
1998-2001  Research Fellowship, Cardiothoracic Surgery
Columbia University College of Physicians and Surgeons, New York, NY
1996-1998  Residency, General Surgery
UCLA Medical School, Los Angeles, CA
1992-1996  MD
Columbia University College of Physicians and Surgeons, New York, NY
1987-1992  BA, Philosophy
Columbia University, New York, NY

Board Certifications

American Board of Thoracic Surgery

Professional Societies and Committees

New York Society of Thoracic Surgeons, Executive Council -- 2009-present

Society for Thoracic Surgeons, Member -- 2008-present

Course Director, TCT for Surgeons -- 2007-present

American College of Cardiology -- 2005-present

American Heart Association, Council on Cardiovascular Surgery -- 1999-2001

International Society of Heart and Lung Transplantation, Member -- 1999

American College of Surgeons, Candidate Group -- 1997-2002

Selected Publications

Garrido MJ, Cheema FH, Willliams MR, Kherani AR, Vigilance DW, Oz MC, Argenziano M. BEAMS: Epicardial Measurements using a benchtop mock-loop system. Journal of Cardiac Surgery, 2009 (in press).

Marques MP, Melo JQ, Knaut M, Alfieri O, Benussi S, Willliams MR, Hornero F, Restoring sinus rhythm in patients with previous pacemaker implantation submitted to cardiac surgery and concomitant surgical ablation of atrial fibrillation. Eur J Cardiothoracic Surg. 2008 Apr;33(4):596-9.

Melo J, Santiago T, Aguiar C, Berglin E, Knaut M, Alfieri, O, Benussi S, Sie H, Williams M, Hornero, F, Marinelli G, Ridley P, Fulquet-Carreras E, Ferreira A. Surgery for atrial fibrillation in patients with mitral valve disease: results at five years from the International Registry of Atrial Fibrillation Surgery. J Thoracic Cardiovascular Surgery 2008 Apr;135 (4):863-9.

Comas GM, Imren Y, Willliams MR. An overview of energy sources in clinical use for the ablation of atrial fibrillation. Semin Thoracic Cardiovasc Surg 2007 Spring; 19(1):16-24.

Hong, KN, Russo MJ, Williams, MR, Abbasi A, Sorabella R, Martens TP, Smith CR Jr, Oz MC, Argenziano, M. Patient-specific characteristics determine success of surgical atrial fibrillation ablation in patients with persistent atrial fibrillation. Heart Surg Forum 2007; 10(6): E468-72.

Hong KN, Russo MJ, Liberman EA, Trzebucki A., Oz MC, Argenziano M., Williams MR. Effect of Epicardial Fat on Ablation Performance: A Three-Energy Source Comparison. Journal of Cardiac Surgery 2007 Nov-Dec; 22(6): 521-4.

Willliams MR, Casher J, Russo MJ et al. Laser energy source in Surgical Atrial Fibrillation Ablation: pre-clinical experience. Ann Thorac Surg. 2006 Dec;82(6):2260-2264.

Magnano AR, Argenziano M, Dizon JM, Vigilance D, Williams M, Yegen H, Rueter K, Oz M, Garan H. Mechanisms of atrial tachyarrhythmias following surgical atrial fibrillation ablation. J Cardiovasc Electrophysiol.2006 Apr;17(4):366-73.

Topkara VK, Williams MR, Barili F, Bastos R, Liu JF, Liberman EA, Russo MJ, Oz MC, Argenziano M, Radiofrequency and microwave energy sources in surgical ablation of atrial fibrillation: a comparative analysis. Heart Surg Forum. 2006;9(3):E614-7.

Williams MR, Russo MJ, Oz MC, Argenziano M, Epicardial cardiac ablation using laser energy. Heart Surg Forum. 2006;9(2):E598-600.

Williams MR, Garrido M, Oz MC, Argenziano M, Alternative energy sources for surgical atrial ablation. Journal of Cardiac Surgery. 19(3):201-6, 2004.

Argenziano M, Williams MR, Robotic atrial septal defect repair and endoscopic treatment of atrial fibrillation. Seminars in Thoracic & Cardiovascular Surgery. 15(2):130-40, 2003.

Morales DL, Garrido MJ, Madigan JD, Helman DN, Faber J, Williams MR, Landry DW, Oz MC, A double-blind randomized trial: prophylactic vasopressin reduces hypotension after cardiopulmonary bypass. Annals of Thoracic Surgery. 75(3):926-30, 2003.

S Maybaum, Williams MR, A Barbone, H Levin, M Oz, D Mancini. Assessment of synchrony relationships between the native ventricle and the heartmate left ventricular assist device. J Heart Lung Transplant. 2002; 21(5):509-15

D Mancini, MC Oz, Williams MR, Cardiac transplantation and circulatory support devices. In: WS Colucci, AM Gotto, ME Josephson, J Lescalzo, S Oparil, JJ Pompa (eds): Cardiovascular Therapeutics. New York: WB Saunders, 2002:374-387.

Williams MR, M Knaut, D Berube, MC Oz, Application of microwave energy in cardiac tissue ablation: from in vitro analyses to clinical use. Ann Thorac Surg. 2002;74:1500-5.

Pass RH, Williams MR, Quaegebeur JM, Liberman L, Hordof AJ, Intraoperative radiofrequency linear catheter ablation of accessory pathways in children with Ebstein's anomaly undergoing tricuspid annuloplasty. American Journal of Cardiology. 90(7):817-9, 2002.

Williams MR, M Argenziano, MC Oz, Microwave ablation for surgical treatment of atrial fibrillation. Seminars in Thoracic and Cardiovascular Surgery. 14(3):232-237, 2002.

Morales DL, Kavarana MN, Helman DN, Madigan JD, Williams MR, Landry DW, Oz MC, Restoration of renal function in shock by perfusion of the renal artery with venous blood: a counterintuitive approach. Critical Care Medicine. 30(6):1297-300, 2002.

Williams MR, P Lo Gerfo, Thyroidectomy using local anesthesia in critically ill patients with amiodarone induced thyrotoxicosis: A review and description of the technique. Thyroid. 2002 Jun;12(6):523-5. Review.

N Viola, Williams MR, MC Oz, N AD, The technology in use for the surgical ablation of atrial fibrillation. Seminars in Thoracic and Cardiovascular Surgery. 14(3):198-205, 2002.

Williams MR, RB Wellner, EA Hartnett, B Thornton, M Kavarana, R Mahapatra, MC Oz, R Sladen, Long term survival and quality of life in cardiac surgical patients with prolonged ICU length of stay. Ann Thorac Surg Annals of Thoracic Surgery. 73(5):1472-8, 2002.

Kavarana MN, Helman DN, Williams MR, Barbone A, Sanchez JA, Rose EA, Oz MC, Milbocker M, Kung RT, Circulatory support with a direct cardiac compression device: a less invasive approach with the AbioBooster device. J Thorac Cardiovasc Surg. 2001 Oct;122(4):786-7.

D’Alessandro D, Barbone A, Burton EA, Rao V, Cabreriza SE, Williams MR, Naka Y, Beck J, Mongero LB, Digiorgi P, Thomas NJ, Boylston BF, Oz MC, Venous blood cardioplegia provides superior preservation of ventricular function in ischemic myocardium. Circulation 104(17); II-473, 2001.

Barbone A, Reiken SR, Holmes J, D’Alessandro DA, Williams MR, Digiorgi P, Naka Y, Marks AR, Burkhoff D, Improved ß-adrenergic responsiveness in RV and LV following LVAD support. Circulation 104(17); II-169, 2001.

Williams MR, Kourpanidis S, Casher J, et al. Epicardial atrial ablation with high intensity focused ultrasound on the beating heart. Circulation 104(17); II-409, 2001.

Kavarana MN, Asher AS, Barbone A, Williams MR, Faber JM, Weinberg AD, Isidro AB, Oz MC, Esrig BC, A comparison of consecutive off-pump versus conventional coronary artery bypass. Heart Surgery Forum. 4(2):160-5, 2001.

MN Kavarana, Williams MR, DN Helman, A Barbone, EA Rose, MC Oz, External cardiac compression device supports circulation without compromising coronary artery bypass graft function J American College of Surgeons, 191:4(Supp 1), S77, 2000.

Selected Presentations


"The epicardial approach to Surgical Atrial Fibrillation Ablation is safe and effective using the laser energy source." NewEra Cardiac Care, Newport Beach, California, January 7, 2006.

"Increased left atrial aize is associated with increased rhythm failure and postoperative stroke following surgical atrial fibrillation ablation" at NewEra Cardiac Care, Newport Beach, CA, January 7, 2006.

"Impact of different energy sources on surgical ablation of atrial fibrillation: A comparative analysis" at NewEra Cardiac Care. Dana Point, CA., January 8, 2005.

"Surgical laser ablation for atrial fibrillation" at Controversies in Cardiac Surgery. Los Angeles, CA. October 7, 2004.

"Surgical treatment of Atrial Fibrillation" at the Coburg- Electrophysiology Meeting. Coburg, Germany,. March 26, 2004.

"Surgical treatment of Atrial Fibrillation" at Cardiostim 2004. Nice, France. June 16, 2004.

"Epicardial radiofrequency lesions are not transmural but can cure atrial fibrillation" at the Society of Thoracic Surgeons, 2004 annual meeting. San Antonio, Texas. January 27, 2004.

"Alternative Energy Sources for Surgical Treatment of Atrial Fibrillation" at the CardiothoracicTechniques and Technologies. Miami, FL, January 26, 2002.

"Alternative Energy Sources and Prediciton of Transmurality for Surgical Treatment of Atrial Fibrillation" at the Emerging Treatments Conference. Orlando, FL, October 26, 2002.

"Alternative Approaches and Energy Sources for Surgical Treatment of Atrial Fibrillation" at the NewEra 2001- NewEra Cardiac Care: Innovation and Technology. Dana Point, CA, January 6, 2001.

"Initial Clinical Experience with Intraoperative Radiofrequency Ablation for Atrial Fibrillation" at the Southern Thoracic Surgical Association, 47th Annual Meeting. Marco Island, FL. November 11, 2000.

"Feasibility of Epicardial Radiofrequency Pulmonary Vein Isolation for Thoracoscopic Treatment of Atrial Fibrillation" at the North American Society of Pacing and Electrophysiology- 21st Annual Scientific Sessions. Washington DC. May 19, 2000.

"Non-sutured Coronary Anastomoses: Are they Ready for Prime Time?" at the NewEra 2000- NewEra Cardiac Care: Innovation and Technology. San Diego, CA, January 14, 2000.

"A Randomized Trial of Antithrombin Concentrate in Heparin Resistant Patients During Cardiopulmonary Bypass" at the American Heart Association- 72nd Scientific Sessions. November 8, 1999.

"Use of Inhaled Nitric Oxide in Cardiac Transplantation" at the International Society for Heart and Lung Transplantation. San Francisco, CA, April 22, 1999.

"Platelet Transfusions are Associated with the Development of Anti-MHC Class I Antibodies in Patients with Left Ventricular Assist Support" at the International Society for Heart and Lung Transplantation, London, UK, April 5, 1997.

"Diode Laser Assisted Solder Reinforcement of Sutured Colon Anastomoses" at the American Society for Laser Medicine and Surgery, San Diego California, April 29-May 1, 1991.

"Preliminary Results with Sutured Colonic Anastomoses Reinforced with Dye-Enhanced Fibrinogen and a Diode Laser" at Progress in Biomedical Optics-The Society for Photo-Optical Instrumentation Engineers, Los Angeles, California, January 21-22, 1991.

(Visit PubMed to view this faculty member's most recent articles.)






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