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Presbyterian Hospital
Room 9E-105
622 West 168th St.
New York, NY   10032

Phone: 212-305-4895

-Columbia University Medical Center
-Department of Medicine
-Division of Pulmonary, Allergy and Critical Care Medicine
-Department of Epidemiology

R. Graham Barr, M.D., Dr.P.H.
Assistant Professor of Medicine and Epidemiology

Research Summary
Novel risk factors for asthma and chronic obstructive pulmonary disease (COPD)

Research Activities
Dr. Barr’s research is primarily in respiratory epidemiology. He has evaluated hormonal and analgesic risk factors for asthma and COPD in the Nurses’ Health Study. He is currently funded to extend the investigations of hormones and asthma and usage of over-the-counter analgesic drugs during asthma exacerbations and their effects on the inflammatory process. He is also co-PI of the Columbia Field Center of the Multi-Ethnic Study of Atherosclerosis (MESA), a large NHLBI-funded cohort study, and a co-investigator of a study of long-term exposure to air pollution in MESA. Dr. Barr is also interested in clinical epidemiology and the use of novel epidemiologic methods, particularly with respect to direct/indirect effects and time series analysis.

Selected Publications:
1. Barr RG, Wentowski CC, Curhan GC, Somers SC, Stampfer MJ, Schwartz J, Speizer FE, Camargo CA Jr (2003) Prospective study of acetaminophen use and newly diagnosed asthma among adult women Am J Respir Crit Care Med :in press

2. Barr RG, Rowe BH, Camargo CA Jr (2003) Methylxanthines for exacerbations of chronic obstructive pulmonary disease: meta-analysis of randomised trials BMJ :in press

3. Barr RG, Wentowski CC, Grodstein F, Somers SC, Stampfer MJ, Schwartz J, Speizer FE, Camargo CA Jr (2003) Prospective study of postmenopausal hormone use and asthma or chronic obstructive pulmonary disease Arch Intern Med :in press

4. Barr RG, Cooper DM, Speizer FE, Drazen JM, Camargo CA Jr (2001) b2-receptor gene polymorphism and body mass index are associated with asthma in sedentary but not active women Chest 120:1474-9

5. Barr RG, Woodruff PG, Clark S, Camargo CA Jr (2000) Sudden-onset asthma exacerbations: clinical features, response to therapy, and 2-week follow-up Eur Respir J 15:266-73

6. Pablos-Méndez A, Barr RG, Shea S (1998) Run-in periods in randomized trials: implications for the applicability of results to clinical practice JAMA 279:222-5

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